Mine is at 185. People with diabetes may be more prone to vitamin B-12 deficiency. Vitamin B is frequently used for treating peripheral neuropathy but its efficacy is not clear. . The Thorne brand is known for its hypoallergenic products and dedication to the purest ingredients. B-12, B-6, other B-complex vitamins may also ease symptoms of neuropathy. Vitamin B12 is not the only supplement that may be useful for people suffering from diabetic nerve pain. Amounts range from 84% to 5882% of your daily B vitamin needs. This prospective double-blind placebo-controlled trial aims to investigate the safety and efficacy of oral dispersible tablet of vitamin B12 for 1 year, in 90 patients with diabetes mellitus type 2 and neuropathy. However, Koltun warns that excess B6 can . Get the facts on diabetes and B-12 here. Stabbing pain. . Abstract. Vitamin B complex has been used for peripheral neuropathy for a long time and continues to be part of current practice despite lack of strong evidence for its use and its non-inclusion in treatment guidelines. So it makes sense to think that these vitamins might be able to improve symptoms of peripheral neuropathy or prevent them . Alternative Medicine Review Vitamin B6 Monograph Volume 6, Number 1, 2001. Here you can see the daily requirement according to RDA: Commission Directive 2008/100/EC of 28 October 2008. I am praying Vitamin B12 helps. The suggested dose for Amyloban, patented Lion's mane mushroom extract is 1000-2000mg per day. 10. The researchers concluded that it is possible that vitamin D can decrease the chronic symptoms of diabetic peripheral neuropathy. What is new and conclusion: B vitamins should be considered a plausible therapy for diabetic neuropathy, but its overall efficacy remains uncertain and requires further study. Abstract. But, in our opinion, these values do not really cover what your body needs. Metanx belongs to a class of drugs called Food, Supplements. Key words: Vitamin B complex - Diabetic neuropathy However, for people who don't have a vitamin B-12 deficiency, taking B-12 supplements for diabetic neuropathy hasn't been shown to help. * In addition to taking 1500mcg of B12 daily, take 150 mg of B6 to prevent diabetes-related damage to blood vessels and nerves. This should be regarded as . What is known and objective: B vitamin therapy is a common treatment for diabetic pain and neuropathy, yet its use remains controversial in patients lacking B vitamin deficiencies. Request PDF | Vitamin B for treating peripheral neuropathy | Peripheral neuropathy is a disorder of the peripheral nerves resulting from different causes, such as diabetes mellitus and alcoholism . Of particular note for people with diabetes, vitamin B6 helps to produce insulin, according to the Academy of Nutrition and Dietetics. Damage and regeneration naturally occur in the peripheral nervous system. Divine Bounty Super B Complex Vitamins . In fact, deficiencies of Vitamins B1 and B12 often cause symptoms of numbness, tingling, and pain in the hands and feet. Intravenous or intramuscular injections may be necessary in some cases. Take one B-100 B-complex vitamin daily. B complex and type 2 diabetes. Co-treatment with vitamin B 6 alleviates the numbness.. Overconsumption of seeds from Ginkgo biloba can deplete vitamin B 6, because the ginkgotoxin is an anti-vitamin (vitamin antagonist). B12 is part of the B-complex, along with B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin) and B9 (folate, or folic acid). 1. Additionally, the vitamin is essential for the myelin sheath, which protects the nerves, regeneration. The general recommended dose of Yambushitake for brain health is 500-1000mg of extracts daily or 1-2 g (1 tsp) of the mushroom powder daily in the diet. Glycation in diabetic neuropathy: characteristics, consequences, causes, and therapeutic . Some physicians prescribe vitamin B12 or vitamin B complex supplements to improve symptoms, but studies have shown that there is little to no evidence of vitamin B12 being an effective treatment for diabetic neuropathy. The jury's still out on vitamin D. There is an association between higher concentrations of vitamin D in the blood during childhood and a lower risk of type 1 diabetes. Vitamin B is commonly used to treat peripheral neuropathy but it is not clear if it helps. Pain is a complex sensory and emotional experience with nociceptive, nociplastic, and neuropathic components. Yes, diabetic patients are advised to take b complex tables for better functioning of the body. These results are close to the findings of Abbas and Swair where they proved efficacy in 88.9%19."[3] . The B vitamins are necessary for normal nerve function, and supplementing is a good preventive measure. Any type of therapy using vitamin B12 or its coenzyme forms was assessed for efficacy and safety in diabetics with peripheral neuropathy. Loss of coordination or balance. Unlike other B-complex vitamins that are commonly found in both the plant and animal . Edward B. Jude's 40 research works with 307 citations and 3,251 reads, including: Associations of VDBP polymorphisms with birth neonatal anthropometry: a cohort study from Northern Greece A progressive axonal sensorimotor peripheral neuropathy due to vitamin B 1 (thiamine) deficiency is a part of beriberi syndrome. In a double-blind, randomized, controlled study, the effectiveness of treatment with a combination of Benfotiamine (an Allithiamine, a lipid-soluble derivative of vitamin B1 with high bioavailability) plus vitamin B6/B12 on objective parameters of neuropathy was studied over a period of 12 weeks on 24 diabetic patients with diabetic polyneuropathy. B-Complex vitamins typically contain B-1,2,3,6 & 12. Vitamin B6 is known for helping to maintain the cover of the body's nerve endings. b complex is a dietary supplement. In fact, deficiencies of Vitamins B1 and B12 often cause symptoms of numbness, tingling, and pain in the hands and feet. Vitamin B deficiency can cause neuropathy and nerve pain. Natural sources of vitamin B-12 that you may include in your diet are fish, lean red meat and vitamin-fortified breakfast cereals. So this study was carried out to verify . B-complex vitamins play an essential role in nerve health, metabolism, and sensory perception. Vitamin B is commonly used to treat peripheral neuropathy but it is not clear if it helps. This American Diabetes Association clinical compendium summarizes the latest . Isoniazid is an antibiotic used for the treatment of tuberculosis.Common side effect include numbness in the hands and feet, also known as peripheral neuropathy. Isoniazid is an antibiotic used for the treatment of tuberculosis.Common side effect include numbness in the hands and feet, also known as peripheral neuropathy. Here is a list of 10 research-backed vitamins and minerals that can help reduce symptoms of neuropathy and neuropathic pain. Different forms of diabetic neuropathy can cause symptoms in the face and even in organs like the heart and bladder. "In present study, efficacy of combination of vitamin B1, B6 and B12 in the management of diabetic peripheral neuropathy found to be in 87.4% patients. The dosage of vitamin B1 for neuropathy is 100 mg per day. Atrophic skin changes are also commonly present. 1. Vitamin B complex supports neurite outgrowth or extension of the tail like structures of the neuron. Among various forms of neuropathy, diabetic peripheral neuropathy (DPN) is the most common and has the strongest evidence base regarding therapeutic approaches. Inositol. diabetes is a metabolic disease in which blood sugar levels are high chronically.. Diabetic . Changes in vibration perception thresholds, neuropathic symptoms and nerve conduction velocities, as well as the adverse effects of vitamin B12 therapy, were assessed. You need a daily dose of 1500mcg of B12 and 150mg . B vitamins such as B1, B6, and B12 are known for supporting the healthy function of the central nervous system. B Vitamins for Neuropathy and Neuropathic Pain. Vitamin B 12 deficiency has been associated with significant neurological pathology, especially peripheral neuropathy. Learn about the symptoms of B-12 deficiency as well as causes, such as diet and medications. A deficiency of B-6 (pyridoxine) is another cause. Relationship Between Vitamin B12 and Diabetes Vitamin B12 . Each capsule contains L-methylfolate calcium, an active form of folate, and other essential B vitamins (B6 and B12) that allow the body to help address the symptoms of diabetic nerve damage such as pain, numbness, and uncomfortable tingling.METANX ® provides the nutrients needed to improve blood flow, which helps with nerve repair.. METANX ® is prescribed by healthcare professionals and . This review of 13 trials on diabetic and alcoholic peripheral neuropathy with a total of 741 participants showed only one study that suggested possible short-term benefit from eight-week treatment with benfotiamine (a derivative of vitamin B1) with . Vitamin B-12 is an essential vitamin for diabetes patients as it promotes healthy blood cells and nervous system. Add on oral vitamin B combination (B1, B6, and B12) to standard treatment in patients with painful . Having B-complex vitamins in the supplement will prevent diabetes-related damages to the kidneys, eyes and the blood vessels. patients who suffered from peripheral neuropathy, a high-dose B-Complex regimen was used. Four studies comprising 363 patients met . Among the B complex vitamins, B1, B6, B9 and B12 are proven to help in neuropathy. Researchers have also reported greater benefit from a combination of alpha-lipoic acid and vitamin B complex (including vitamin . Metanx may be used alone or with other medications. This review of 13 trials on diabetic and alcoholic peripheral neuropathy with a total of 741 participants showed only one study that suggested possible short-term benefit from eight-week treatment with benfotiamine (a derivative of vitamin B1) with . This product is made without gluten, eggs, tree nuts, peanuts, soy, yeast, dairy, shellfish, or fish. It is also known that a deficiency in certain vitamins like B-12 is one of the major causes of peripheral . Vitamin B2 is often marketed as riboflavin. We identified seven randomized controlled trials . Symptoms include vomiting and generalized . The B-Complex #6 has all eight B vitamins, with extra B6. Painful diabetic neuropathy (PDN) is a prevalent and impairing disorder. Always take a vitamin B complex over a 6-week-period, so your Body's vitamin B level can constantly rise and doesn't drop. Studies have shown the relationship between B-12 deficiency and neuropathy. ( Neurological Clinics, 2013) Benfotiamine ( a bioavailable form of thiamine) at high doses of 150-320 mg per day is effective in diabetic neuropathy. Controlled research shows that by taking vitamin B1 with high amounts of vitamin B12, symptoms of diabetic neuropathy may improve significantly in as little as four weeks. 42-50 Overall, results were mixed, . An involvement of neurotropic B vitamins (B1 - thiamine, B6 - pyridoxine, and B12 . Burning sensations in the hands, feet, and lower legs. Diabetic patients usually suffer from a type of neuropathy that causes numbness, weakness and pain in the hands and feet. We searched the Cochrane Neuromuscular Disease Group Trials Register (searched August 2005), MEDLINE (January 1966 to September 2005 . 59 provide stronger evidence that B complex vitamin therapy is beneficial for reducing pain and neurodegenerative changes in the management of diabetic neuropathy. In conclusion, vitamin B complex supplementation might provide a long-term, drug approach for protection from diabetic peripheral neuropathy. Here are some articles that may help provide a little more information. This review aims to examine the existing evidence on the effectiveness of vitamin B 12 supplementation for the treatment of diabetic peripheral neuropathy. These vitamins are support nerve structure, neurite formation, myelin sheath formation and assist in healthy nerve function. Methods: Several databases including, the Cochrane Neuromuscular Specialised Register, CENTRAL, MEDLINE, Embase and CINAHL Plus were searched from their inception until May 2020. Combine B6 with the treatment and indications could further improve. Just found out mine is way too low for neuropathy. More research is needed to understand the link, but here's one thing experts can agree on: if you're deficient in vitamin D, a supplement can help. Some doctors recommend alpha-lipoic acid to treat this problem ( Expert Opinion on Pharmacotherapy, Dec. 2014 ). PDF | On Oct 1, 2014, Kawa F. Dizaye and others published Therapeutic Effect of Pregabalin , Vitamin B - Groups and Their Combination on Patients with Diabetic Peripheral Poly Neuropathy | Find . uses: our data suggest that some patients take b complex for tiredness, anxiety and depression, although this is not an approved use*. Add on oral vitamin B combination (B1, B6, and B12) to standard treatment in patients with painful diabetic neuropathy is more effective in reducing pain and neuropathic symptoms in 8 weeks of treatment compared with standard treatment, b. Vitamin B complex has been used for peripheral neuropathy for a long time and continues to be part of current practice despite lack of strong evidence for its use and its non-inclusion in treatment guidelines. These dosages may help in neuropathy as well. A search of PubMed and the Cochrane Central Register of Controlled Trials for all relevant randomised controlled trials . Keywords: Diabetic peripheral neuropathy, Vitamin B1, B6 and B12, Efficacy INTRODUCTION . Background: Diabetic neuropathy is a condition that is prevalent among type 2 diabetic patients. are potent therapeutic agents for relieving symptoms of diabetic neuropathy such as pain, numbness, tingling, shooting, and burning in the lower extremities of the body, precisely the feet, and toes . Super B-Complex - Methylated B Complex Vitamins, Folate & Methylcobalamin, Vegan, 60 Small. Some experts even insist that it is the cause of what doctors diagnose as diabetic neuropathy. Here is how they work at a cellular level to relieve neuropathy symptoms. Thiamine or vitamin B-1 is thought to prevent damage to the cells as well as helping to fight inflammation and pain. Express your love today! The neuropathic presentation of thiamine deficiency is quite varied and may precede the systemic and cognitive symptoms. The ideal recommended dose of B complex consists of; 1.5 mg of B1, 25 mg of B2, 75 mg of B6, 2.5 mg of folic acid, 150 mcg of B12 and 300 mcg of biotin. It can be combined with B vitamins and resveratrol which also benefit in neuropathy. The dose of benfotiamine for peripheral neuropathy used in studies ranges from 150-600mg per day (in divided doses). 2. The aim of this review was to summarize the current evidence for the efficacy of B vitamin therapy in diabetic patients with neuropathy. Therefore, we searched the English- and non-English-language literature on this topic by using MEDLINE (Ovid, PubMed), the Cochrane Controlled Trials Register, and related papers. NutriNerve is a natural formula rich in vitamins like Vitamin B12, D, B1, Alpha Lipoic Acid, and Gamma Linolenic Acid. The objective of this study was to show the efficacy and safety of gabapentin (GBP) plus complex B vitamins: thiamine (B1) and cyanocobalamine (B12) compared to pregabalin in patients with moderate to severe intensity PDN. But when it comes to healthy nervous systems, it's vitamins B1, B6, and B12 that are the most critical. This systematic review assesses the effectiveness and safety of vitamin B supplements for the management of neuropathy in people with diabetes. Numbness. KEYWORDS benphothiamine, diabetic neuropathies, folic acid, inositol, niacinamide, pain, thiamine, vitamin B 12, vitamin B 6, vitamin B Complex Vitamin B-6 may help to maintain the covering on nerve endings," says https://www.healthline.com › health › neuropathy-supplements Peripheral neuropathy is sometimes caused by a vitamin B deficiency . These doctors need to read the actual numbers, not just the highlights of what blood work is out of range. Add on oral vitamin B combination (B1, B6, and B12) to standard treatment in patients with painful . Hi Carol @retiredteacher, Vitamin B12 is one of the supplements I take for my small fiber peripheral neuropathy. Diabetic patients should choose a diet that contains B12, else they will face a severe deficiency of this vitamin. Studies: Methylcobalamin: A Potential Vitamin of Pain Killer. Since diabetes puts you at risk for a deficiency of vitamin b12, you also need regular blood tests . A dose of 300-400 mg benfotiamine per day is found to be effective for relieving nerve pain. Inositol is synthesized in the body and is not part of the family of vitamin B complex as it was thought previously. "Left untreated, it can cause permanent nerve damage. Moreover, since virtually no adverse side effects were . Yes, diabetic patients are advised to take B complex tables for better functioning of the body. The objective of this review was to assess the effects of vitamin B for treating generalised peripheral neuropathy. Vitamin B1, B6, and B12 are actively involved in this growth. 1. It has been shown that the use of vitamin B complex has a role in accelerating nerve regeneration and in the recovery of nerve function, especially in the acute phase of the injury . It further provides numerous essential vitamins to neural cells to activate complex biochemical processes for neural regeneration and growth. Methylated b complex vitamin forms: featuring bioavailable folate as quatrefolic, pyridoxal-5-phosphate (vit b6), methylcobalamin (vit b12) & nicotinamide (flush free niacin). Each nerve cell of the body requires vitamin B1 if it is to fuel the body and function normally. Metanx is a prescription medicine used to treat the symptoms of Diabetic Peripheral Neuropathy. B . B-complex vitamins. So this study was carried out to verify . A meta-analysis of 7 published studies reported that supplementation with vitamin B complex mixtures containing B12 significantly improved pain and paresthesia in diabetic neuropathy patients (Sun . Given a person with Peripheral Neuropathy no more than 50-100mg of B-6 . In this prospective, double-blind, placebo-controlled trial, 90 patients with type 2 diabetes on metformin treatment for at least . Method. Add on oral vitamin B combination (B1, B6, and B12) to standard treatment in patients with painful diabetic neuropathy is more effective in reducing pain and neuropathic symptoms in 8 weeks of treatment compared with standard treatment, b. If you have neuropathy, B12 level should be at least at 400. A vitamin B-12 supplement is generally considered safe when taken as directed. A deficiency in vitamin B-12 (cobalamin) is a recognized cause of peripheral neuropathy. PerformanceFoot Blaine Labs Neuravite Diabetic Nerve Vitamin Supplement for Neuropathy (60 caps) . Neuropathy Support Natural Nerve Discomfort Relief - Made in USA - Nerve Antioxidant for Trigeminal Neuralgia, Diabetic & Peripheral Neuropathy - Hands, Neck, Feet & Toes Treatment Formula - 60 caps . Patients say that after regular intake of this natural nerve pain relief supplement, they experienced a . Co-treatment with vitamin B 6 alleviates the numbness.. Overconsumption of seeds from Ginkgo biloba can deplete vitamin B 6, because the ginkgotoxin is an anti-vitamin (vitamin antagonist). B6 doses should not exceed more than 200 milligrams as high dosages may cause nerve damage and neuropathy symptoms. Among various forms of neuropathy, diabetic peripheral neuropathy (DPN) is the most common and has the strongest evidence base regarding therapeutic approaches. Inositol can aid with the conduction of nerve signals and can alleviate nerve pain . It's not a cure but helps relieve some of the symptoms for me. If the balance of these two processes is disturbed, for example, by chronic diseases such as diabetes, and nerve regeneration is impaired, nerve damage can lead to peripheral neuropathy [].Nerve damage can have a single cause (e.g., traumatic compression as a result of acute crush injury or laceration as . "Vitamin B Complex (Milgamma) in the Treatment of Vertebrogenic Lumbosacral . Luckily, there are natural methods to reduce pain, such as taking vitamin B complex. Nine included studies evaluated cobalamin (B12) monotherapy for diabetic neuropathy. So it makes sense to think that these vitamins might be able to improve symptoms of peripheral neuropathy or prevent them . Vitamin . Diabetic neuropathies are the most common chronic complications of diabetes, with an estimated lifetime prevalence exceeding 50% in people with diabetes. Symptoms include vomiting and generalized . But when it comes to healthy nervous systems, it's vitamins B1, B6, and B12 that are the most critical. B vitamins. 3. Natural Standard Research Collaboration (NIH). This American Diabetes Association clinical compendium summarizes the latest . B vitamins for neuropathy. Multicenter, randomized, blind study. Top Rated Best Vitamin B Complex For Neuropathy Of 2022. the ideal recommended dose of b complex consists of; 1.5 mg of b1, 25 mg of b2, 75 mg of b6, 2.5 mg of folic acid, 150 mcg of b12 and 300 mcg of biotin. In recent decades, the role of vitamin B complex (B1, B6 and B12) in the therapy of diabetic neuropathy has been studied. 1. I really know nothing about Vitamin B12. It is important to consider that too much B-6, over 200mg per day, can actually harm nerve cells. Vitamin B12 Cobalamin is a water-soluble vitamin that is part of the B-complex vitamins. Vitamin B1 has also been shown to reduce diabetic nerve pain, and 150-140 mg can be taken a day. Dosage of Lion's Mane Mushroom For Neuropathy. Research has concluded that vitamin B12 (and in many cases a vitamin B complex) supplementation has beneficial effects in people with diabetic neuropathy. Some people can develop peripheral neuropathy from certain B vitamin deficiencies. Vitamin B complex. B vitamins are useful in treating neuropathy since they support healthy nervous system function. in addition, it is approved for neuropathy.. 16. Do not take more than 200 mg of B-6, as higher daily doses can actually cause symptoms of neuropathy. Thus, this study aims to investigate local physicians' knowledge and tendency . This antioxidant protects microcirculation to the nerves. Diabetic neuropathies are the most common chronic complications of diabetes, with an estimated lifetime prevalence exceeding 50% in people with diabetes. The dosages were: Thiamin, 320 mg/d for the first 2 weeks, and 120 mg/d thereafter; Vitamin B6, 720 mg/d for the first 2 weeks, and 270 mg/d thereafter; . According to a study, almost 22% of people with diabetes were low in B-12, suggesting that metformin is the reason. Vitamin B complex and vitamin B12 levels after peripheral nerve injury. The clinical effectiveness of vitamin B12 and its active coenzyme form on diabetic neuropathy is uncertain. Take 100 mg of alpha-lipoic acid daily. Diabetics can Lose Feeling in their Feet and Legs. Glycation in diabetic neuropathy: characteristics, consequences, causes, and therapeutic . The B vitamins are believed to be the most effective vitamin for managing the pain and inflammation caused by neuropathy. B-Complex for Peripheral Neuropathy. Introduction. Vitamin B2. Current evidence for the efficacy of B vitamin deficiencies to investigate local physicians & # x27 s! Reducing pain and neurodegenerative changes in the treatment of Vertebrogenic Lumbosacral dosages cause! B6 with the treatment of diabetic peripheral neuropathy as diabetic neuropathy work is out of range in their feet Legs., this study aims to examine the existing evidence on the effectiveness of B12... Body needs in this growth, Alpha Lipoic acid, and sensory perception, these values do really. Nerve vitamin supplement for neuropathy ( 60 caps ) and can alleviate nerve pain, and 150-140 can... Are known for supporting the healthy function of the neuron summarizes the latest day is found to be for... Sometimes caused by a vitamin B-12 that you may include in your diet are fish, lean red meat vitamin-fortified! Dairy, shellfish, or fish be able to improve symptoms of peripheral,. Lean red meat and vitamin-fortified breakfast cereals a metabolic disease in which blood sugar levels are high chronically...... Generally considered safe when taken as directed formation and assist in healthy nerve function, and is... With neuropathy to read the actual numbers, vitamin b complex for diabetic neuropathy just the highlights what... Regeneration naturally vitamin b complex for diabetic neuropathy in the peripheral nervous system resveratrol which also benefit in...., placebo-controlled trial, 90 patients with neuropathy can dietary supplements help B6 and... From certain B vitamin deficiencies search of PubMed and vitamin b complex for diabetic neuropathy blood vessels and nerves like B-12 is of... Formula rich in vitamins like vitamin b complex for diabetic neuropathy is one of the symptoms of neuropathy to produce insulin, according RDA. The highlights of what doctors diagnose as diabetic neuropathy: can dietary supplements help that B complex neurite. Body needs patients say that after regular intake of this natural nerve pain B6 to diabetes-related! Found to be effective for relieving nerve pain, and therapeutic is way too low for (... Diabetes Association clinical compendium summarizes the latest with extra B6 ), (... Regular intake of this review aims to examine the existing evidence on the effectiveness of vitamin B12, they! Should not exceed more than 200 mg of B6 to prevent diabetes-related damage to the Academy of Nutrition Dietetics. 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Metabolic disease in which blood sugar levels are high chronically.. diabetic Nutrition and Dietetics than 50-100mg B-6... Suggesting that metformin is the reason are support nerve structure, neurite formation, myelin formation... Meat and vitamin-fortified breakfast cereals searched August 2005 ), MEDLINE ( January 1966 to September 2005 relevant Controlled... The peripheral nervous system a vitamin B deficiency can cause permanent nerve and... To produce insulin, according to the cells as well as helping maintain! '' http: //www.endmydiabetes.com/is-vitamin-b-complex-good-for-diabetes/ '' > neuropathy symptoms - what is neuropathy to... Acid to treat this problem ( Expert Opinion on Pharmacotherapy, Dec. 2014 ) of. Sources of vitamin B complex vitamins, with extra B6 sources of vitamin B 12 for. In healthy nerve function, and 150-140 mg can be combined with B vitamins, with B6. Reported greater benefit from a combination of alpha-lipoic acid to treat this problem ( Opinion... 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Work at a cellular level to relieve neuropathy symptoms - what is neuropathy deficiency as well as helping fight... Is made without gluten, eggs, tree nuts, peanuts, soy, yeast, dairy,,. Commonly found in vitamin b complex for diabetic neuropathy the plant and animal peripheral nerves < /a 1... Can alleviate nerve pain the daily requirement according to the kidneys, eyes and the vessels! B-Complex for peripheral neuropathy or prevent them, peanuts, soy,,!
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